|
|
 |
 |
|
Introduction
Course Overview
Fundamental concepts
The event profile of a runaway
Data requirements for safety assessment
Desired and undesired chemistry
The Chemical Hazard Potential
Desk-top Thermal Hazards Screening
Figures of Merit of Thermally Unstable Materials
Auto-catalysis and the chemistry of energetic materials
Characterization of the Thermal Runaway Reaction
The importance of thermokinetics data
Rates of heat and pressure generation
The heat balance
The Phi factor
Safe process scale-up
Parameters used to characterize thermal runaway in batch reactors
Case studies and incident investigations
Principles of Reactive Hazards Testing
Characteristic Thermal Safety Data
Principle of similarity
Immediate requirements on testing
Normal process characterizations
Adiabatic techniques for runaway simulation
Comparison of Calorimeters: Do the right job.
Safety Measure Selection
Criteria for the assessment of thermal risk
Defining critical limits
Prevention and protection techniques
Deciding upon a basis of safety
Applications taken from the literature
Use of TMR theory to plan an intervention strategy
Thermal risk of a process modification
Synthesis of diazonium salt
Designing a safer nitration reaction
Estimating the safe storage temperature using laboratory-scale tests
Systematic risk analysis of a Grignard reaction
Introduction to Emergency Relief Systems
Venting as a basis of safety
The problem of two-phase flow from venting runaways
|
|
