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Chemical Reaction Hazards Guide

Chemical Reaction Hazards and Thermally Unstable Substances: A Strategic Guide to Reaction Hazard Assessment

The consequences of runaway exothermic chemical reactions can be devastating. Catastrophes at Bhopal and Seveso are stark reminders that all chemical processes require a thorough and rigorous assessment procedure to ensure that large scale manufacture can proceed without residual risk or threat of disaster.

This guide outlines a cost-effective mechanism for assessing hazards present in the inherent exothermic reaction and uncontrolled gas evolution potential of chemical processes. We cover:

  • The PreVent methodology for reaction hazards testing
  • Route selection, process development, and optimization
  • Assessment of explosive properties, gas generation, and thermal stability
  • Approaches for pilot, small-scale, and full-scale facilities
  • Overview and description of available test procedures